The National Heart, Lung, and Blood Institute (NHLBI) of the National Institutes of Health has stopped a clinical trial studying the benefits and safety of administering a highly concentrated form of saline solution in the ambulance
(before hospital arrival) to trauma patients suffering from shock due to severe bleeding.

The trial was stopped because patients who received the concentrated saline solutions were no more likely to survive than those who received a normal saline solution. A parallel study of concentrated saline for traumatic brain injury without shock continues.