Simulation has long been recognized for the integral role it plays in high-risk industries. As the Ebola virus disease is amply demonstrating, health care is a high-risk industry. Yet providers and health care workers should not have to put their own lives at risk when caring for the sickest patients. Several simulation centers are already initiating simulation-based preparations to optimize their own readiness for Ebola patients and more rigorously address essential training, protocol development, personal protective equipment, and facilities issues. A new issue brief by the Agency for Healthcare Research and Quality's (AHRQ) underscores the helpful role simulation can serve in response to the Ebola virus disease, other emergent epidemic challenges, provider and patient safety, and quality of care in general. In addition to tested and verified protocols, health care professionals need practice implementing them through simulation. This brief also addresses simulation's essential features and benefits, approaches and uses. For more information click here.